DICL_CP_0307040 - DICL Database

Basic Molecular Information

Basic Information

DICL ID

DICL_CP_0307040

PubChem CID

750

Molecular Formula

C₂H₅NO₂

Molecular Weight

75.067 g/mol

Synonyms/Alias

[glycine; 56-40-6; 2-Aminoacetic acid; aminoacetic acid; Glycocoll; Aminoethanoic acid; Glycolixir; H-Gly-OH; Glicoamin; Glycosthene; Aciport; Padil; L-Glycine; Hampshire glycine; Amitone; Leimzucker;...[glycine; 56-40-6; 2-Aminoacetic acid; aminoacetic acid; Glycocoll; Aminoethanoic acid; Glycolixir; H-Gly-OH; Glicoamin; Glycosthene; Aciport; Padil; L-Glycine; Hampshire glycine; Amitone; Leimzucker; Aminoazijnzuur; Acetic acid; amino-; Glycine; non-medical; Sucre de gelatine; Glycinum; GLY (IUPAC abbrev); Gyn-hydralin; Corilin; Glicina; Glycine [INN]; Glyzin; FEMA No. 3287; Acido aminoacetico; Glycinum [INN-Latin]; Acide aminoacetique; Glicina [INN-Spanish]; Acidum aminoaceticum; gly; Glykokoll; Aminoessigsaeure; Hgly; CCRIS 5915; HSDB 495; Acide aminoacetique [INN-French]; Acido aminoacetico [INN-Spanish]; Acidum aminoaceticum [INN-Latin]; 25718-94-9; AI3-04085; NSC 25936; GLYCINE 1.5% IN PLASTIC CONTAINER; H2N-CH2-COOH; amino-Acetic acid; EINECS 200-272-2; UNII-TE7660XO1C; MFCD00008131; NSC-25936; [14C]glycine; TE7660XO1C; DTXSID9020667; CHEBI:15428; Glycine [USP:INN]; NSC25936; CHEMBL773; DTXCID90667; Glycine iron sulphate (1:1); EC 200-272-2; aminoacetate; Athenon; 2-aminoacetate; Glycine (USP:INN); NCGC00024503-01; Glycinum (INN-Latin); Glicina (INN-Spanish); GLYCINE (II); GLYCINE [II]; GLYCINE (MART.); GLYCINE [MART.]; Glycine; free base; GLYCINE (USP-RS); GLYCINE [USP-RS]; GLYCINE (EP MONOGRAPH); GLYCINE [EP MONOGRAPH]; GLYCINE (USP MONOGRAPH); GLYCINE [USP MONOGRAPH]; Acide aminoacetique (INN-French); Acido aminoacetico (INN-Spanish); Acidum aminoaceticum (INN-Latin); GLYCINE-1-13C-15N; CAS-56-40-6; Glycine; labeled with carbon-14; AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER; Aminoessigsaure; Aminoethanoate; 18875-39-3; amino-Acetate; Glycine;; 2-aminoaceticacid; [3H]glycine; Glycine USP grade; Glycine; EP/USP; H-Gly; L-Gly; Gly-CO; Gly-OH; L-Glycine;(S); [14C]-glycine; Corilin (Salt/Mix); Tocris-0219; Glycine (H-Gly-OH); GLYCINE [VANDF]; NH2CH2COOH; GLYCINE [FHFI]; GLYCINE [HSDB]; Glycine; >=99%; GLYCINE [FCC]; GLYCINE [JAN]; GLYCINE [MI]; Glycine (JP17/USP); Glycine; 99%; FCC; GLYCINE [WHO-DD]; Biomol-NT_000195; bmse000089; bmse000977; WLN: Z1VQ; Gly-253; GLYCINE [GREEN BOOK]; GTPL727; AB-131/40217813; GLYCINE [ORANGE BOOK]; Treating Gingivitis Toothpaste; Glycine; Electrophoresis Grade; BPBio1_001222; GTPL4084; GTPL4635; Repair Cracked Teeth Toothpaste; BDBM18133; AZD4282; Glycine; >=99.0% (NT); Glycine; 98.5-101.5%; Pharmakon1600-01300021; Glycine 1000 microg/mL in Water; 2-Aminoacetic acid;Aminoacetic acid; BCP25965; CS-B1641; HY-Y0966; Glycine; ACS reagent; >=98.5%; Tox21_113575; Glycine; 99%; natural; FCC; FG; HB0299; NSC760120; s4821; STL194276; Glycine; purum; >=98.5% (NT); Glycine; tested according to Ph.Eur.; AKOS000119626; Glycine; for electrophoresis; >=99%; Tox21_113575_1; AM81781; CAREDO Treating Gingivitis Toothpastes; CCG-266010; DB00145; NSC-760120; Glycine - Absolute carbon isotope ratio; Glycine; BioUltra; >=99.0% (NT); Glycine; BioXtra; >=99% (titration); SERINE IMPURITY B [EP IMPURITY]; CAREDO Repair Cracked Teeth Toothpastes; Glycine; SAJ special grade; >=99.0%; NCGC00024503-02; NCGC00024503-03; BP-31024; Glycine; Vetec(TM) reagent grade; 98%; CAREDO Treating Gingivitis Toothpastes100g; DB-029870; G0099; G0317; Glycine; ReagentPlus(R); >=99% (HPLC); NS00001575; CAREDO Repair Cracked Teeth Toothpastes100g; EN300-19731; A20662; C00037; D00011; D70890; M03001; L001246; Q620730; SR-01000597729; Glycine; certified reference material; TraceCERT(R); Q-201300; SR-01000597729-1; Q27115084; B72BA06C-60E9-4A83-A24A-A2D7F465BB65; F2191-0197; Glycine; European Pharmacopoeia (EP) Reference Standard; Z955123660; Glycine; BioUltra; for molecular biology; >=99.0% (NT); InChI=1/C2H5NO2/c3-1-2(4)5/h1;3H2;(H;4;5; Glycine; United States Pharmacopeia (USP) Reference Standard; Glycine; Pharmaceutical Secondary Standard; Certified Reference Material; Glycine; analytical standard; for nitrogen determination according to Kjeldahl method; Glycine; from non-animal source; meets EP; JP; USP testing specifications; suitable for cell culture; >=98.5%; Glycine; meets analytical specification of Ph. Eur.; BP; USP; 99-101% (based on anhydrous substance)]

InChI Key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

InChI

InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

IUPAC Name

2-aminoacetic acid

CAS Number

N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation

2D Molecular Drawing

Carbon (C)

Hydrogen (H)

Oxygen (O)

Nitrogen (N)

Sulfur (S)

SDF

10 9 0 0 0 0 0 0 0 0999 V2000
-0.5806 -0.3085 -0.1815 C 0 0 0 0 0 0 0 0 0 0 0 0
0.9127 -0.2690 -0.1427 C 0 0 0 0 0 0 0 0 0 0 0 0
1.5448 -1.037...

Download SDF File (894 bytes)

Experimental Data

Activity Data

Target Ion Channel

Glycine receptor alpha-2

Uniprot Accession Number

P23416

Function

Agonist

Species

Homo sapiens (Human)

IC₅₀

N/A (Not available)

EC₅₀

EC₅₀: 97000 nM

K_i

N/A (Not available)

K_d

N/A (Not available)

Inhibition

N/A (Not available)

Experimental Conditions

pH 7.3

Holding Potential

−60 mV mV

Temperature

25 °C

Test Method

Patch-clamping

Test Species

HEK293 cell (Homo sapiens embryonic kidney 293 cell)

Binding Information

Binding Site

Extracellular domain

Binding Site Residue

F174, F223, common binding region on αH1 and αH2 subunits

Disease Information

Related Disease

Not specified

References

DOI

10.1111/j.1469-7793.2001.t01-1-00741.x

URL

N/A (Not available)

PMID

11559772

Patent

N/A (Not available)

Computed Properties

Heavy Atom Count

Rotatable Bonds

logP

-0.9703

Complexity

16.6902

TPSA (Å²)

63.32

H-Bond Donors

H-Bond Acceptors

Ring Count

New Search

Molecular Details

Basic Molecular Information

Basic Information

Structure Information

Chemical Structure Visualization

Experimental Data

Activity Data

Experimental Conditions

Binding Information

Disease Information

References

Computed Properties